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CCG273441

Cat. No: CDIA-0762

CAS. No.: 2750414-35-6

Size: 5 mg

Price: Inquiry

Product Details
Formula	C26H24ClFN4O3
Molecular Weight	494.95
Appearance	Solid
Purity	98.67%
Smiles String	O=C(/C(C1=C2)=C\C3=C(C(NC(CCl)=O)=C(N3)C)C)NC1=CC=C2C(N[[email protected]@H](C4=CC=C(C=C4)F)C)=O

Storage & Handling
Shipping	Room temperature.
Storage Powder	-20 °C/3 years, 4 °C/2 years

Description

CCG273441 is a covalent inhibitor of G protein-coupled receptor (GPCR) kinase 5 (GRK5) with an IC50 value of 3.8 nM. CCG273441 is highly selective to GRK5 over GRK2 (IC50=4.8 μM) by binding Cys474, a GRK5 subfamily-specific residue, as a covalent handle.

! For research use only. Not intended for any clinical use.