Cyclic ADP-​ribose

Product Details
Formula	C15H21N5O13P2
Molecular Weight	541.30
Appearance	Solid
Purity	≥96.0%
Smiles String	O[[email protected]]([[email protected]@H]1O)[[email protected]](O[[email protected]]1([H])COP(O)(OP(O)(OC2)=O)=O)([H])N3C(N=CN([[email protected]]4([H])O[[email protected]@]2([H])[[email protected]@H](O)[[email protected]]4O)C5=N)=C5N=C3

Storage & Handling
Shipping	Shipping with dry ice.
Storage	-80 °C

Cyclic ADP-ribose (cADPR) is a potent second messenger for calcium mobilization that is synthesized from NAD+ by an ADP-ribosyl cyclase. Cyclic ADP-ribose increases cytosolic calcium mainly by Ryanodine receptor-mediated release from endoplasmic reticulum and also by extracellular influx through the opening of TRPM2 channels.

! For research use only. Not intended for any clinical use.