Dabigatran (ethyl ester)

Product Details
Formula	C27H29N7O3
Molecular Weight	499.56
Appearance	Solid
Purity	≥98.0%
Smiles String	O=C(N(C1=NC=CC=C1)CCC(OCC)=O)C2=CC=C3C(N=C(N3C)CNC4=CC=C(C(N)=N)C=C4)=C2

Storage & Handling
Shipping	Room temperature.
Storage Powder	-20 °C/3 years, 4 °C/2 years

Dabigatran ethyl ester is an emerging oral anticoagulant which is a direct inhibitor of thrombin activity. IC50 value: Target: thrombin Dabigatran provides a stable anticoagulation effect without any need to perform periodical laboratory controls. Of note, there is a growing amount of clinical evidence which shows its safety and efficacy. For these reasons, Dabigatran may suppose a revolution in oral anticoagulation. Dabigatran etexilate was rapidly converted to Dabigatran, with peak plasma dabigatran concentrations being attained after approximately 1.5 h; the bioavailability of Dabigatran after p.o. administration of Dabigatran etexilate was 7.2%.

! For research use only. Not intended for any clinical use.