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Dooku1

Cat. No: CDIA-0037

CAS. No.: 2253744-54-4

Size: 1 mg

Price: Inquiry

Product Details
Formula	C13H9Cl2N3OS
Molecular Weight	326.20
Appearance	Solid
Purity	99.89%
Smiles String	ClC1=C(C(Cl)=CC=C1)CSC2=NN=C(C3=CC=CN3)O2

Storage & Handling
Shipping	Room temperature.
Storage	-20 °C, sealed storage, away from moisture *In solvent : -80 °C, 6 months; -20 °C, 1 month (sealed storage, away from moisture)

Description

Dooku1, an analog of Yoda1, is a selective antagonist of the endogenous Piezo1 channel. Dooku1 inhibited 2 μM Yoda1-induced Ca2+-entry with IC50 values of 1.3 μM (in HEK 293 cells) and 1.5 μM (in HUVECs). Dooku1 inhibits Yoda1-induced relaxation of aorta.

! For research use only. Not intended for any clinical use.