FXR agonist 4

Product Details
Formula	C21H28ClN3O
Molecular Weight	373.92
Smiles String	ClC1=CC(N2CCN(C(C34C[[email protected]@H]5C[[email protected]](C4)C[[email protected]@H](C5)C3)=O)CC2)=C(N)C=C1

Storage & Handling
Shipping	Room temperature.
Storage	Please refer to the instruction manual.

FXR agonist 4 (compound 10a) is an agonist of farnesoid X receptor (FXR) with an EC50 value of 1.05 μM. FXR agonist 4 effectively improves hyperlipidemia, hepatic steatosis, insulin resistance and hepatic inflammation in DIO mice. FXR agonist 4 can be used for the research of non-alcoholic fatty liver disease (NAFLD).

! For research use only. Not intended for any clinical use.