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GSK484 hydrochloride

Cat. No: CDIA-0051

CAS. No.: 1652591-81-5

Size: 1 mg

Price: Inquiry

Product Details
Formula	C27H32ClN5O3
Molecular Weight	510.03
Appearance	Solid
Purity	99.72%
Smiles String	O=C(N1C[[email protected]](N)[[email protected]](O)CC1)C2=CC(OC)=C3C(N=C(C(N4CC5CC5)=CC6=C4C=CC=C6)N3C)=C2.[H]Cl

Storage & Handling
Shipping	Room temperature.
Storage	4 °C, stored under nitrogen *In solvent : -80 °C, 6 months; -20 °C, 1 month (stored under nitrogen)

Description

GSK484 hydrochloride is a selective and reversible peptidylarginine deiminase 4 (PAD4) inhibitor. GSK484 hydrochloride demonstrates high affinity binding to PAD4 with IC50s of 50 nM in the absence of Calcium. In the presence of 2 mM Calcium, notably lower potency (250 nM) is observed.

! For research use only. Not intended for any clinical use.