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hTTR

Cat. No: CDM0102

Nomenclature: C57BL/6N-Ttr^tm1(hTTR)

Strain State: Embryo cryopreservation

Gene Summary
Human Ortholog	TTR
MGI ID	98865
Gene ID	7276
Target Name	TTR
Synonyms	CTS, TTN, ATTR, CTS1, PALB, TBPA, HEL111, HsT2651

Model Description
Description	These humanized TTR mice carry a 7.2-kb replacement of the entire murine Ttr locus—from 7.2 kb upstream through the 3′ UTR—with the cognate human TTR sequence.
Disease Connection	Transthyretin Amyloidosis (ATTR)
Phenotype(s)	6110836

! For research use only. Not intended for any clinical use.