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KR-39038

Cat. No: CDIA-0778

CAS. No.: 2770300-35-9

Size: 10 mg

Price: Inquiry

Product Details
Purity	98.65%

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Description

KR-39038 is an orally active and potent GRK5 (G protein-coupled receptor kinase 5) inhibitor, with an IC50 of 0.02 μM. KR-39038 significantly inhibits angiotensin II-induced cellular hypertrophy through suppression of HDAC5 pathway in neonatal cardiomyocytes. KR-39038 shows profound anti-hypertrophic effects and improved cardiac function. KR-39038 can be used for heart failure research.

! For research use only. Not intended for any clinical use.