Online Inquiry
Recombinant Cynomolgus 5'-Nucleotidase/CD73/NT5E Protein (His Tag)
| Target Information | |
|---|---|
| Target Name | 5'-Nucleotidase/CD73/NT5E |
| Synonyms | 5'-Nucleotidase; 5'-NT; Ecto-5'-Nucleotidase; CD73; NT5E; NT5; NTE |
| UniProt ID | F7DLG4 |
| Accession | G7P3J1 |
| Product Details | |
|---|---|
| Expression Host | HEK293 Cells |
| Species | Cynomolgus macaques |
| Tag | C-His |
| Molar Mass | 58.8 kDa |
| Sequence | Ser 31-Lys 243 |
| Background |
|---|
| CD73, also known as Ecto-5'-nucleotidase, is an ectoenzyme that is attached to the cell membrane by a glycosyl phophatidylinositol anchor. The enzyme is expressed by most cell types. The 5’-Nucleotidase activity of CD73 converts extracellular nucleoside-5’-monophosphates to nucleosides. CD73 is one of several enzymes responsible for the production of extracellular adenosine, a signaling molecule that is involved in responses to inflammation and tissue injury. CD73 hydrolyzes extracellular nucleotides into membrane permeable nucleosides. |
| Properties | |
|---|---|
| Purity | >97% as determined by reducing SDS-PAGE. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 120 mM NaCl, 4 mM CaCl2, 20% Glycerol, pH7.5. |
| Reconstitution | Please refer to the printed manual for detailed information. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. |
| Storage | Store at < -20 °C, stable for 6 months. Please minimize freeze-thaw cycles. |
! For research use only. Not intended for any clinical use.