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Recombinant Human ATG4A Protein (His Tag)
| Target Information | |
|---|---|
| Target Name | ATG4A |
| Synonyms | Cysteine Protease ATG4A; AUT-Like 2 Cysteine Endopeptidase; Autophagin-2; Autophagy-Related Cysteine Endopeptidase 2; Autophagy-Related Protein 4 Homolog A; hAPG4A; ATG4A; APG4A; AUTL2 |
| UniProt ID | Q99988 |
| Accession | Q8WYN0 |
| Product Details | |
|---|---|
| Expression Host | E.coli |
| Species | Human |
| Tag | N-6His |
| Molar Mass | 47.5 kDa |
| Sequence | Ser 2-Pro 531 |
| Background |
|---|
| Cysteine Protease ATG4A (ATG4A) is a cytoplasmic protein that belongs to the peptidase C54 family. ATG4A is widely expressed in many tissues at a low level, but the highest expression is observed in skeletal muscle and brain. ATG4A is a cysteine protease required for autophagy; it cleaves the C-terminal part of MAP1LC3, GABARAPL2 or GABARAP. ATG4A is inhibited by N-ethylmaleimide. It is suggested that ATG4A has a significant role in suppressing various cancers. |
| Properties | |
|---|---|
| Purity | >97% as determined by reducing SDS-PAGE. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20 mM PBS, 150 mM NaCl, pH7.4. |
| Reconstitution | Please refer to the printed manual for detailed information. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. |
| Storage | Store at < -20 °C, stable for 6 months. Please minimize freeze-thaw cycles. |
! For research use only. Not intended for any clinical use.