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Recombinant Human FABP5 Protein

Cat. No : CDRP-00939

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Price: Online Inquiry

Target Information
Target Name	FABP5
Synonyms	Fatty Acid-Binding Protein Epidermal; Epidermal-Type Fatty Acid-Binding Protein; E-FABP; Fatty Acid-Binding Protein 5; Psoriasis-Associated Fatty Acid-Binding Protein Homolog; PA-FABP; FABP5
UniProt ID	Q08830
Accession	Q01469

Product Details
Expression Host	E.coli
Species	Human
Tag	None
Molar Mass	15.2 kDa
Sequence	Met 1-Ala 132

Background
Fatty acid-binding protein; also known as Epidermal-type fatty acid-binding protein; Fatty acid-binding protein 5; Psoriasis-associated fatty acid-binding protein homolog; E-FABP and FABP5; is a cytoplasm protein which Belongs to thecalycin superfamily and Fatty-acid binding protein (FABP) family. Fatty acid-binding proteins ( FABPs ) are postulated to serve as lipid shuttles that solubilize hydrophobic fatty acids and deliver them to appropriate intracellular sites. E-FABP/FABP5 is predominantly expressed in keratinocytes and is overexpressed in the actively proliferating tissue characteristic of psoriasis and wound healing. E-FABP/ FABP5 exhibits an important role in binding free fatty acids; as well as regulating lipid metabolism and transport. E-FABP/FABP5 has high specificity for fatty acids. It has highest affinity for C18 chain length. Decreasing the chain length or introducing double bonds reduces the affinity of FABP5. E-FABP /FABP5 may be involved in keratinocyte differentiation.

Background

Fatty acid-binding protein; also known as Epidermal-type fatty acid-binding protein; Fatty acid-binding protein 5; Psoriasis-associated fatty acid-binding protein homolog; E-FABP and FABP5; is a cytoplasm protein which Belongs to thecalycin superfamily and Fatty-acid binding protein (FABP) family. Fatty acid-binding proteins ( FABPs ) are postulated to serve as lipid shuttles that solubilize hydrophobic fatty acids and deliver them to appropriate intracellular sites. E-FABP/FABP5 is predominantly expressed in keratinocytes and is overexpressed in the actively proliferating tissue characteristic of psoriasis and wound healing. E-FABP/ FABP5 exhibits an important role in binding free fatty acids; as well as regulating lipid metabolism and transport. E-FABP/FABP5 has high specificity for fatty acids. It has highest affinity for C18 chain length. Decreasing the chain length or introducing double bonds reduces the affinity of FABP5. E-FABP /FABP5 may be involved in keratinocyte differentiation.

Properties
Purity	>95% as determined by reducing SDS-PAGE.
Formulation	Lyophilized from sterile 50 mM Tris, pH8.0.
Reconstitution	Please refer to the printed manual for detailed information.
Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Storage	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 °C. Reconstituted protein solution can be stored at 4-8 °C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 °C for 3 months.

! For research use only. Not intended for any clinical use.