Products

Online Inquiry

* First Name

* Last Name

Phone

* Business Email

Company/Institution

Job Title

* Services or Products of Interest

When do you expect your project to start?

Project Description

* Please note that all of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

Rodatristat ethyl

Cat. No: CDIA-1072

CAS. No.: 1673571-51-1

Synonyms: KAR5585

Size: 5 mg

Price: Inquiry

Product Details
Formula	C29H31ClF3N5O3
Molecular Weight	590.04
Appearance	Solid
Smiles String	ClC1=CC(C2=CC=CC=C2)=C([[email protected]@H](OC3=NC(N)=NC(N4CCC5(CN[[email protected]](C(OCC)=O)C5)CC4)=C3)C(F)(F)F)C=C1

Storage & Handling
Shipping	Room temperature.
Storage Powder	-20 °C/3 years, 4 °C/2 years

Description

Rodatristat ethyl (KAR5585) is a first-in-class oral tryptophan hydroxylase 1 (TPH1) Inhibitor with nanomolar in vitro potency. Rodatristat ethyl reduces the level of 5-HT and significantly reduces pulmonary arterial hypertension (PAH).

! For research use only. Not intended for any clinical use.