Products

Online Inquiry

* First Name

* Last Name

Phone

* Business Email

Company/Institution

Job Title

* Services or Products of Interest

When do you expect your project to start?

Project Description

* Please note that all of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

Safinamide mesylate

Cat. No: CDIA-0654

CAS. No.: 202825-46-5

Synonyms: FCE 26743 mesylate; EMD 1195686 mesylate

Size: 5 mg

Price: Inquiry

Product Details
Formula	C18H23FN2O5S
Molecular Weight	398.45
Appearance	Solid
Purity	99.87%
Smiles String	C[[email protected]](NCC1=CC=C(OCC2=CC=CC(F)=C2)C=C1)C(N)=O.CS(=O)(O)=O

Storage & Handling
Shipping	Room temperature.
Storage	4 °C, sealed storage, away from moisture *In solvent : -80 °C, 6 months; -20 °C, 1 month (sealed storage, away from moisture)

Description

Safinamide (FCE 26743; EMD 1195686) mesylate is a potent, selective, and reversible monoamine oxidase B (MAO-B) inhibitor (IC50=0.098 µM) over MAO-A (IC50=580 nM). Safinamide mesylate also blocks sodium channels and modulates glutamate (Glu) release, showing a greater affinity at depolarized (IC50=8 µM) than at resting (IC50=262 µM) potentials. Safinamide mesylate has neuroprotective and neurorescuing effects and can be used for the study of parkinson disease, ischemia stroke et.al.

! For research use only. Not intended for any clinical use.