SCH-42354

Product Details
Formula	C16H23NO3S2
Molecular Weight	341.49
Smiles String	CSCC[[email protected]@H](C(O)=O)NC([[email protected]@H](CS)CC1=C(C=CC=C1)C)=O

Storage & Handling
Shipping	Room temperature.
Storage	Please refer to the instruction manual.

SCH-42354 is a potent, orally active neutral endopeptidase (NEP) inhibitor, is the pharmacologically active form of the proagent SCH-42495. SCH-42354 inhibits the hydrolysis of NEP to enhance the activity of atrial natriuretic peptide (ANP). SCH-42354 inhibits hydrolysis of leu-enkephalin and ANF with IC50 values of 8.3 nM and 10.0 nM, respectively. SCH-42354 has antihypertensive activity.

! For research use only. Not intended for any clinical use.