Cardiac Organoid Models

Cardiac organoids are self assembling, three dimensional multicellular constructs derived from human induced pluripotent stem cells (iPSCs). In cardiovascular preclinical research, organoids are rapidly emerging as a transformative bridge between conventional 2D culture and in vivo animal models, enabling human specific disease phenotyping, high content mechanistic interrogation, and early de risking of drug candidates.

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Our Services for Cardiac Organoids

Cardiotoxicity & Proarrhythmic Risk Assessment
Comprehensive evaluation of small molecules, biologics, and novel drug candidates is performed using multi‑electrode array (MEA) field‑potential recordings and intracellular calcium imaging.
Drug Screening & Lead Optimization
Medium‑ to high‑throughput screening panels are available for the identification of inotropic, anti‑fibrotic, or anti‑arrhythmic compounds.
Developmental Toxicology
Early‑stage screening for teratogenic or embryotoxic effects of candidate compounds is offered in the context of cardiogenesis, enabling proactive safety de‑risking.
Combinatorial & Multi‑modality Testing
Concurrent evaluation of drug‑device combinations, nanocarrier formulations, and photodynamic therapies is supported using integrated organoid‑on‑chip platforms that enable dynamic dose control and real‑time endpoint acquisition.

Cardiac Organoid Models

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Cardiac Organoid Models

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