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hPCSK9
Cat. No: CDM0103
Nomenclature: C57BL/6N-Pcsk9tm1(hPCSK9)
Strain State: Embryo cryopreservation
| Gene Summary | |
|---|---|
| Human Ortholog | PCSK9 |
| MGI ID | 2140260 |
| Gene ID | 255738 |
| Target Name | PCSK9 |
| Synonyms | FH3, PC9, FHCL3, NARC1, LDLCQ1, NARC-1, HCHOLA3 |
| Model Description | |
|---|---|
| Description | These mice achieve a complete replacement of the murine Pcsk9 coding sequence with its human PCSK9 ortholog. |
| Disease Connection | Hypercholesterolemia, Atherosclerosis, Coronary Heart Disease, Stroke, Alzheimer's Disease |
| Phenotype(s) | 8176256 |
! For research use only. Not intended for any clinical use.