Sanggenon C

Product Details
Formula	C40H36O12
Molecular Weight	708.71
Appearance	Solid
Purity	97.30%
Smiles String	C/C(C)=C/C[[email protected]](C1=CC=C(O)C=C1O2)(OC3=CC(O)=C([[email protected]@H](C=C(C)C[[email protected]@H]4C(C=CC(O)=C5)=C5O)[[email protected]@H]4C(C(C=CC(O)=C6)=C6O)=O)C(O)=C3C7=O)[[email protected]]27O

Storage & Handling
Shipping	Room temperature.
Storage	-20 °C, sealed storage, away from moisture and light *In solvent : -80 °C, 6 months; -20 °C, 1 month (sealed storage, away from moisture and light)

Sanggenon C is a flavanone Diels-Alder adduct compound, which is isolated from Cortex Mori (Sang Bai Pi). Sanggenon C exerts protective effects against cardiac hypertrophy and fibrosis via suppression of the calcineurin/NFAT2 pathway. Sanggenon C inhibits inducible nitric oxide synthase expression in RAW264.7 cells, and tumor necrosis factor-α-stimulated cell adhesion and vascular cell adhesion molecule-1 expression, by suppressing NF-κB activity. Sanggenon C possesses antioxidant, anti-inflammatory activities and inhibits Pancreatic lipase (PL) with the an IC50 of 3.00 μM.

! For research use only. Not intended for any clinical use.