Simvastatin acid-d6 (ammonium)

Product Details
Formula	C25H37D6NO6
Molecular Weight	459.65
Smiles String	O=C(C[[email protected]@H](C[[email protected]@H](CC[[email protected]@]1([H])[[email protected]](C=CC2=C[[email protected]@H](C[[email protected]@H]([[email protected]]12[H])OC(C(CC)(C([2H])([2H])[2H])C([2H])([2H])[2H])=O)C)C)O)O)[O-].[NH4+]

Storage & Handling
Shipping	Room temperature.
Storage	Please refer to the instruction manual.

Simvastatin acid-d6 (ammonium)mis the deuterium labeled Simvastatin acid ammonium. Simvastatin ammonium is an active metabolite of simvastatin lactone mediated by CYP3A4/5 in the intestinal wall and liver (pKa=5.5). Simvastatin ammonium reduces indoxyl sulfate-mediated reactive oxygen species and modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 gene.

! For research use only. Not intended for any clinical use.