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Tpm1-E180G

Cat. No: CDM0111

Nomenclature: C57BL/6J-Tpm1^{em1Cin (E180G)}

Strain State: Embryo cryopreservation

Gene Summary
Human Ortholog	TPM1
MGI ID	98809
Gene ID	7168
Target Name	Tpm1
Synonyms	AA986836, AI854628, TM2, TPM1kappa, Tm3, Tmpa, Tpm-1, alpha-TM

Model Description
Description	These mice carry a cardiac-specific transgene encoding human TPM1 (α-tropomyosin) with the E180G mutation causally linked to hypertrophic cardiomyopathy type 3.
Disease Connection	Myocardial Hypertrophy, Heart Failure
Phenotype(s)	5906030

! For research use only. Not intended for any clinical use.