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Preclinical Ophthalmic Drug Development Services

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Preclinical Drug Development

As a leading solution provider in ophthalmology, Ace Therapeutics is committed to providing comprehensive ophthalmology solutions to advance and support your project development. Here, we provide comprehensive and systematic ophthalmic drug preclinical research services. This will help you meet any challenges you may encounter at this significant stage of drug development.

Understanding the Challenges in Ophthalmic Drug Development

Ocular Disease Models

Lack of preclinical ophthalmology models capable of simulating human ocular pathology.

Ocular Disease Models

Our preclinical eye disease models cover various ocular diseases and involve multiple animal species. We also provide model customization services and a series of supporting services to meet your project needs.

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Ocular Drug Delivery Systems

Difficulty for drugs to penetrate the corneal barrier.

Ocular Drug Delivery Systems

Our team of experts is committed to developing multiple ocular drug delivery systems for anterior and posterior segment diseases.

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Ocular Toxicity Testing

High sensitivity of ocular tissues to toxicity.

Ocular Toxicity Testing

We provide a variety of ophthalmic toxicology testing services, including assessment of acute, subacute, and chronic local toxicity, determination of the maximum tolerated dose (MTD), and testing of ocular tolerability, to support your ophthalmic drug development project.

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Specialized Services for Diverse Ophthalmic Needs

Ophthalmic Drug Discovery Services
Ophthalmic Pharmacology Testing Services
Ophthalmic Pharmacokinetic Services
Ocular Histology and Histopathology Services
Customized Non-GLP Ophthalmic Program Development Services
Ocular Biospecimen Services
Ocular Biomarker and Bioanalysis Services

Ophthalmic Drug Discovery Services

Ace Therapeutics has a professional research team to provide comprehensive drug discovery services for ocular diseases, including but not limited to small molecule ophthalmic drug discovery, gene therapy development, stem cell therapy development, and tissue-engineered cornea development.

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Ophthalmic Pharmacology Testing Services

We provide ophthalmology drug testing services to evaluate the efficacy of your drug candidates. Our customized in vivo ocular disease models and comprehensive ocular dosing services are designed to conduct in vivo ocular drug studies and evaluate your ophthalmic products.

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Ophthalmic Pharmacokinetic Services

Using biochemical and molecular techniques, we assist researchers in analyzing drug distribution in ocular cells and tissues, investigating drug mechanisms and pharmacological properties, and providing scientific support for drug development and optimization.

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Ocular Histology and Histopathology Services

Our team of experts has experience in evaluating ocular histopathology studies, offering critical insights into the underlying causes of ocular diseases. The key areas of our ocular histopathology services include histopathological analysis, microscopy analysis, immunohistochemical analysis, molecular pathology analysis, and impression cytology analysis.

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Customized Non-GLP Ophthalmic Program Development Services

With extensive expertise in ophthalmology, we provide customized program development services to our clients. Our customized non-GLP ophthalmic program development services range from supporting clients with early pilot studies and proofs-of-concept to the implementation of preclinical GLP projects.

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Ocular Biospecimen Services

Ocular biospecimen analysis is a critical part of eye disease drug development. We provide ocular biospecimen services to assist our clients in elucidating ophthalmic disease mechanisms, identifying new ocular biomarkers, and evaluating potential therapies for eye diseases.

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Ocular Biomarker and Bioanalysis Services

Specializing in ophthalmic biomarker development, we offer comprehensive solutions tailored to your research needs. Our expertise covers discovery, screening, identification, analysis, and translation of biomarkers, supporting decision-making and reducing project development risk.

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What Our Clients Say

"Their innovative use of continuous intraocular pressure telemetry in preclinical glaucoma studies uncovered circadian fluctuation patterns critical to our neuroprotection strategy, enabling data-driven candidate selection months ahead of schedule."

"Their hyperspectral imaging in preclinical retina drug testing captured microvascular dynamics we couldn’t visualize before, refining our lead candidate’s therapeutic window with unprecedented clarity. "

"Their multi-species retinal degeneration models in translational ophthalmic research pinpointed conserved inflammatory pathways, guiding our neuroprotective candidate optimization."

Pharmaceutical Company

Therapeutic Areas in Ophthalmology

Glaucoma

A group of optic neuropathy eye diseases that is characterized by progressive optic nerve degeneration and corresponding visual field loss.

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Glaucoma

Dry Eye Disease

Known as keratoconjunctivitis sicca, dry eye syndrome (DES), and dry eye, is a common chronic disease that affects many people worldwide.

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Dry Eye Disease

Age-Related Macular Degeneration (AMD)

The third leading cause of blindness worldwide, is the leading cause of vision loss in older adults.

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Age-Related Macular Degeneration

Cataract

An eye disease that is characterized by clouding of the lens, including congenital cataracts and age-related cataracts.

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Cataract

Diabetic Retinopathy (DR)

One of the common complications of diabetes that can lead to proliferative retinopathy, macular edema, and eventually blindness.

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Diabetic Retinopathy

Uveitis

Various intraocular inflammatory diseases that occur in the uvea (iris, ciliary body, choroid) and its adjacent structures.

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Uveitis

Retinal Detachment

The separation of the neurosensory retina (NSR) from the underlying retinal pigment epithelium (RPE), is a vision-threatening condition.

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Retinal Detachment

Refractive Errors

A phenomenon that occurs when the eye is unable to focus light from an object onto the plane of the retina, resulting in blurred images.

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Refractive Errors

Conjunctivitis

Known as pink eye, is an infection of the conjunctiva (the outermost eye layer covering the sclera).

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Conjunctivitis
Specialize in Ophthalmology

Frequently Asked Questions

What types of preclinical ophthalmic services do you offer?

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We provide a wide array of preclinical ophthalmic services, covering ocular disease model development, drug discovery, and preclinical drug development.

Do you provide custom-designed research solutions?

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Yes, we provide custom-designed research solutions to meet specific client needs and project requirements.

What preclinical models do you use for different ocular diseases?

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We utilize a variety of advanced models, including in vitro ophthalmic models and in vivo animal models, to simulate different ocular diseases.

What techniques do you employ for drug delivery to the eye?

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We employ various techniques such as topical administration, intravitreal injection, and sustained-release formulations for effective drug delivery.

What imaging technologies do you utilize for ophthalmic studies?

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We use advanced imaging technologies like OCT and fundus photography to monitor and analyze ocular conditions.

Partner in Preclinical Ophthalmic Research

Ace Therapeutics is your trusted partner in preclinical ophthalmic research, supporting your drug development projects.

CONTACT US

Online Inquiry

You can contact us any way that is convenient for you. We are available via email or our online contact form below. Please feel free to reach out with any questions or inquiries.

We would be happy to answer your questions.

Ace Therapeutics is a research service provider specializing in ophthalmology. We are dedicated to providing exceptional research services that support drug development programs for clients worldwide.

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