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SPHINX31

Cat. No: CDIA-0140

CAS. No.: 1818389-84-2

Size: 1 mg

Price: Inquiry

Product Details
Formula	C27H24F3N5O2
Molecular Weight	507.51
Appearance	Solid
Purity	99.12%
Smiles String	O=C(NC1=C(N2CCN(CC3=CC=CC=N3)CC2)C=CC(C(F)(F)F)=C1)C4=CC=C(O4)C5=CC=NC=C5

Storage & Handling
Shipping	Room temperature.
Storage Powder	-20 °C/3 years, 4 °C/2 years

Description

SPHINX31 is a potent and selective SRPK1 inhibitor, with an IC50 of 5.9 nM. SPHINX31 inhibits phosphorylation of serine/arginine-rich splicing factor 1 (SRSF1). SPHINX31 also decreases the mRNA expression of pro-angiogenic VEGF-A165a isoform. SPHINX31 can be used to research neovascular eye disease.

! For research use only. Not intended for any clinical use.