Drug Development for Stroke

WELCOME Ace Therapeutics

We Are the Leading Preclinical CRO Company for Stroke

Ace Therapeutics is an innovative CRO company focusing in early drug discovery services from target validation to preclinical candidate identification and efficacy evaluation, with strong capabilities and technologies in the stroke field.

Our goal is to help pharmaceutical companies complete their research programs faster and more successfully, and find effective therapies for stroke.

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OUR SERVICES

Pharmaceutical R&D For Stroke

Ace Therapeutics is committed to the preclinical phase of stroke drug development, covering everything from model construction, target identification to preclinical candidates and beyond with the flexibility required. We offer a broad portfolio of services and a global network of partners that enable us to provide end-to-end services for small molecule and biomolecule drug discovery in stroke.

Biomarker Identification and Screening Drug Efficacy Testing in Animal Stroke Model Cell-based Assay Safety Assessment ADME DMPK Mechanism of Action Analysis Biophysical Analysis Medicinal Chemistry Integration Compound Screening Cascade Primary Screening Assay Development Protein Production Target Validation Preclinical Candidate Lead Optimization Hit-to-Lead Hit Identification Target Research

Stroke is a disease that affects the arteries leading to and within the brain. Ace Therapeutics has deep expertise and extensive research experience in the field of stroke, providing a wide range of products and services to support basic research and drug development efforts in stroke. Key types of stroke therapy R&D include:

Ischemic and hemorrhagic strokes exhibit neurological dysfunction due to various pathophysiological mechanisms, which provide you with reliable targets to seek more promising stroke treatments.

Excitotoxicity

  • Glutamate release
  • ↓Glutamate uptake
  • Ca2+/Na+ influx
  • Necrosis
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Neuroinflammation

  • DAMPs release(HMGB1)
  • Glial cells activation
  • ↑Leukocytes infiltration
  • Cytokines production
  • BBB disruption
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Oxidative Stress

  • Mitochondrial dysfunction
  • ROS and RNS production
  • Lipid peroxidation
  • ↓ATP synthesis
  • DNA fragmentation
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Angiopathy

  • lnterruption of blood flow
  • Cerebral edema
  • ↑Intracranial pressure
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WHY CHOOSE US

Grow Your Research With Experience

Ace Therapeutics has a proven, full-service model that has been delivering quality results for years, giving your stroke trial a competitive edge. The Ace Therapeutics team supports the development of therapeutics for the treatment of stroke through the use of our in-house resources including:

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Professionals

Deep expertise and experience in vascular research and development.
2

Customization

Flexible approach with easy access to our global network of specialized laboratories. State-of-the-art technology provides you with a fully customized service.
3

Well-equipped

Our fully equipped laboratories have comprehensive capabilities from initial screening to candidate selection.
4

After Sales Service

Solving any problems or concerns that customers may have and ensuring the proper functioning of the product or service.
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