Lipids have emerged as potential biomarkers for various diseases. Since lipids are structural components of cell membranes, signaling mediators, cellular barriers, and energy depots, they can reflect pathological or physiological states of metabolic disorders. In the central nervous system, lipids and lipid mediators play a key role in maintaining the structure and function of brain tissue. To a large extent, they can influence the prognosis and recovery of stroke patients. A better understanding of the functional activities of different lipid molecules provides an opportunity to understand the role of lipids in stroke pathogenesis and to identify novel lipid biomarkers and therapeutic targets.
Fig. 1. Lysophosphatidylcholines and phosphatidylcholines as biomarkers for stroke recovery. (Huang et al., 2022)
Ace Therapeutics offers comprehensive lipid biomarker development services to help clients identify novel biomarkers that can e used to detect, diagnose, and classify stroke. Working closely with our clients, our team of experts investigates the lipids that are associated with physiological responses or the development of stroke.
Our lipid biomarker development services include support for each step of the lipid biomarker research workflow.
Low-density lipoprotein cholesterol | Triglyceride-to-high-density-lipoprotein cholesterol ratio | Oxylipin |
Lipoprotein-associated phospholipase A2 | Lipoprotein (a) | Apolipoprotein A-I |
Apolipoprotein B | Total cholesterol | Triglycerides |
High-density lipoprotein-cholesterol | Low-density lipoprotein-cholesterol | Lysophosphatidylcholines |
Ace Therapeutics offers comprehensive lipid biomarker discovery and validation to help you make informed decisions in your stroke drug development. We have the experience to provide you with a full range of technical support. Please do not hesitate to contact us if you have any questions.
We are committed to accelerating progress in stroke research and drug development.