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Intraluminal Filament tMCAO Model

The transient intraluminal filament MCAO model is a widely used experimental method to mimic focal cerebral ischemia followed by reperfusion, enabling the study of disease mechanisms and potential therapies. At Ace Therapeutics, the mice, rats, and non-human primates (NHPs) are subjected to intraluminal filament tMCAO models to support preclinical stroke research.

Unlock Insights into Stroke Research with Our Intraluminal Filament tMCAO Model Case Study

This poster contains modeling principles and methods, animal species selection, workflow, and efficacy evaluation data of intraluminal filament MCAO model. By integrating advanced and validated methods, Ace Therapeutics ensures that your research is supported by scientifically rigorous data, enhancing the credibility and reproducibility of your findings in stroke drug discovery.

Authoritative Model Analysis

Delves into the pathogenesis of intraluminal filament MCAO models, highlighting their unique advantages in simulating focal cerebral ischemia followed by reperfusion. Serves as a reliable platform for ischemic stroke mechanism research and drug development.

Clearly Visible tMCAO Modeling Diagram

Provides a detailed and easily interpretable representation of the procedure, allowing researchers to visualize the precise steps involved in inducing focal cerebral ischemia followed by reperfusion.

Reliable Efficacy Evaluation Data in the tMCAO Model

Focuses on core experimental outcomes, providing directly applicable empirical support for protocol design:

  • Neurological deficits evaluation: An objective measure of motor and sensory function recovery using the Zea-Longa score.
  • Cerebral infarct volume measurements: Facilitated by TTC (2,3,5-triphenyltetrazolium chloride) staining, offer the visualization of ischemic tissue, ensuring accurate quantification of damage and infarct progression.

Download now to elevate your stroke research with Ace Therapeutics' expertly curated photochemically-induced stroke model brochure—your key to unlocking breakthroughs in ischemic stroke therapeutics!

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