Cat. No.: DMM-001248
| Status | Age | Sex |
|---|---|---|
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| Model Overview | |
|---|---|
| Model Description | These mice harbor knock-out mutations in both the Akt2 (thymoma viral proto-oncogene 2) and Ldlr (low density lipoprotein receptor), and may be useful in studies of diabetes, metabolism, hyperglycemia, and atherosclerosis. |
| Strain Name | B6.129-Akt2tm1.1Mbb Ldlrtm1Her/J |
| Background Strain | C57BL/6J |
| SPF | Yes |
| Research Application | Diabetes |
| Target Information | |
|---|---|
| Target Name | Ldlr |
| Synonyms | LDLCQ2, FHCL1, Low density lipoprotein receptor |
| Gene ID | 3949 |
Ace Therapeutics has a team of experts in the field of endocrine and metabolic research, aiming to provide innovative preclinical contract research solutions to cope with diabetes and its complications. We provide customized solutions and technical support, enabling the transformation of promising concepts into innovative treatments, thus accelerating the drug development process of diabetes.