Diabetic cataract is a serious ocular complication caused by diabetes that severely impairs vision health. Early and accurate diagnosis is crucial for timely intervention and slowing disease progression. However, current conventional diagnostic methods have limitations in sensitivity, specificity, and early diagnostic capability, necessitating the development of more efficient and accurate novel diagnostic approaches. Ace Therapeutics offers specialized diagnostic method development services for diabetic cataracts based on our extensive preclinical research experience and cutting-edge technology in the field of diabetes.
Currently, the diagnosis of diabetic cataract mainly relies on routine ophthalmologic examinations, such as visual acuity examination, slit lamp microscopy, fundus photography and optical coherence tomography (OCT). Although these methods can assist the diagnosis to a certain extent, there are many shortcomings. For example, visual acuity examination is easily influenced by subjective factors, and it is difficult to detect small lesions in the early stage. Slit-lamp microscopy relies on the doctor's experience and carries the risk of missed diagnosis, and imaging tests such as OCT can provide structural information but are expensive and difficult to popularize. In addition, these methods are difficult to accurately quantitatively assess the developmental stage of the disease and cannot meet the demand for personalized diagnosis and treatment.
In order to break through the bottleneck of traditional diagnostic methods, we focus on several cutting-edge directions to carry out diagnostic method development and research services.
Biomarker detection technology
Based on the results of the previous biomarker research in diabetic cataract, we are developing detection methods centered on metabolites, cytokines, proteins and other biomarkers. For example, we can detect the level of specific cytokines in serum or atrial fluid by high-sensitivity immunoassay technology, and establish diagnostic models by combining with artificial intelligence algorithms to realize early screening and accurate diagnosis of the disease.
Optimization of image diagnosis technology
Deep learning algorithms are used to analyze fundus images and OCT images to automatically identify the characteristic lesions of diabetic cataract and improve diagnostic efficiency and accuracy. Meanwhile, we explore multimodal image fusion technology to integrate different image information and reflect the lesions more comprehensively.
Non-invasive testing technologies
We develop non-invasive and convenient tests, such as diagnostic methods based on tear composition analysis. By detecting biomolecules in tears that are associated with diabetic cataracts, we enable rapid, non-invasive diagnosis of the disease.
We specialize in the development and rigorous validation of innovative diagnostic methods for diabetic cataracts.
We provide a variety of diabetic cataract animal model construction services, including streptozotocin-induced rat models, transgenic mouse models and so on. Our customized animal models can provide reliable experimental subjects for the development and validation of diagnostic methods.
We assist our clients in the collection of animal model samples, using standardized procedures to ensure sample quality. Advanced sample processing techniques, such as ultra-high-speed centrifugation and solid-phase extraction, are used to pre-treat the samples and lay the foundation for subsequent testing.
We carry out the development of diagnostic methods using a combination of molecular biology, bioinformatics, imaging and other technologies. We ensure the accuracy, reliability and significance of the developed diagnostic methods by thoroughly validating them.
Ace Therapeutics is committed to providing professional services and cutting-edge technologies to help our clients succeed in the development of diabetic cataract diagnostics. Contact us today for a customized diagnostic method development solution.
Ace Therapeutics has a team of experts in the field of endocrine and metabolic research, aiming to provide innovative preclinical contract research solutions to cope with diabetes and its complications. We provide customized solutions and technical support, enabling the transformation of promising concepts into innovative treatments, thus accelerating the drug development process of diabetes.