B6.129S7- Gck^tm1Ts /J

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B6.129S7- Gck^tm1Ts /J

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B6.129S7- Gck^tm1Ts /J

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Cat. No.: DMM-001266

Status	Age	Sex
Live Mouse Frozen Embryo	4 weeks 12 weeks Customized Age	Male Female

Model Overview
Model Description	The Gcktm1Ts targeted mutation is lethal to homozygous mice perinatally, accompanied by severe hyperglycemia. Heterozygous mice have elevated blood glucose and impaired insulin secretion.
Strain Name	B6.129S7-Gcktm1Ts/J
Background Strain	129S7/SvEvBrd-Hprt1
SPF	Yes
Research Application	Diabetes

Target Information
Target Name	Gck
Synonyms	FGQTL3, GK, GLK, Gls006, GLUKA, hexokinase 4, HHF3, HK4, HKIV, Hlb62, HXKP, LGLK, MODY2, PNDM1, RNGK2
Gene ID	2645

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

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Ace Therapeutics has a team of experts in the field of endocrine and metabolic research, aiming to provide innovative preclinical contract research solutions to cope with diabetes and its complications. We provide customized solutions and technical support, enabling the transformation of promising concepts into innovative treatments, thus accelerating the drug development process of diabetes.

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