B6.BKS(D)-Leprdb/J mouse

B6.BKS(D)-Leprdb/J mouse

Cat. No.: DMM-001241

Status Age Sex
  • Live Mouse
  • Frozen Embryo
  • 4 weeks
  • 12 weeks
  • Customized Age
  • Male
  • Female
Model Overview
Model Description Mice homozygous for the diabetes spontaneous mutation (Leprdb) become identifiably obese around 3 to 4 weeks of age with elevations of plasma insulin beginning at 10 to 14 days and of blood sugar at four to eight weeks. Affected mice are polyphagic, polydipsic, and polyuric.
SPF Yes
Research Application Diabetes
Target Information
Target Name Lepr
Synonyms OBR, CD295, HuB219, LEP-R
Gene ID 3953
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