B6.Cg-Dock7m Leprdb/+ +/J mouse

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B6.Cg-Dock7m Leprdb/+ +/J mouse

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B6.Cg-Dock7m Leprdb/+ +/J mouse

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Cat. No.: DMM-001246

Status	Age	Sex
Live Mouse Frozen Embryo	4 weeks 12 weeks Customized Age	Male Female

Model Overview
Model Description	These mice carry a spontaneous mutation at the Lepr locus on a C57BL/6J background and are characterized by compensatory hyperplasia of the islet B-cells and hyperinsulinemia. Wound healing is delayed, and metabolic efficiency is increased. The strain carries the misty mutation (Dock7m) to aid in early identification of homozygotes.
Strain Name	B6.Cg-Dock7m Leprdb/+ +/J
Background Strain	C57BL/6J
SPF	Yes
Research Application	Diabetes

Target Information
Target Name	Lepr
Synonyms	OBR, CD295, HuB219, LEP-R
Gene ID	3953

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

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Ace Therapeutics has a team of experts in the field of endocrine and metabolic research, aiming to provide innovative preclinical contract research solutions to cope with diabetes and its complications. We provide customized solutions and technical support, enabling the transformation of promising concepts into innovative treatments, thus accelerating the drug development process of diabetes.

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