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B6.Cg-Tg(ACTA1-Scd1)282Ptn/J
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B6.Cg-Tg(ACTA1-Scd1)282Ptn/J

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Cat. No.: DMM-001275

Status Age Sex
  • Live Mouse
  • Frozen Embryo
  • 4 weeks
  • 12 weeks
  • Customized Age
  • Male
  • Female
Model Overview
Model Description These transgenic animals overexpress mouse Scd1 (stearoyl-Coenzyme A desaturase 1) under the control of the human skeletal muscle-specific alpha actin promoter (ACTA1). Animals display significantly increased treadmill exercise capacity, running farther and longer than Wild-type mice. Fatty acid composition of the muscle reveals a striking increase in polyunsaturated fatty acid (PUFA) content of triglycerides.
Strain Name B6.Cg-Tg(ACTA1-Scd1)282Ptn/J
Background Strain FVB/N x 129
SPF Yes
Research Application Diabetes
Target Information
Target Name Tg(ACTA1-Scd1)282Ptn
Synonyms -
Gene ID -
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