BKS.Cg- Dock7m Leprdb /+ +/J

BKS.Cg- Dock7m Leprdb /+ +/J

Cat. No.: DMM-001287

Status Age Sex
  • Live Mouse
  • Frozen Embryo
  • 4 weeks
  • 12 weeks
  • Customized Age
  • Male
  • Female
Model Overview
Model Description These mice carry a spontaneous mutation at the Lepr locus on a C57BLKS/J background and are characterized by obesity, elevation of blood sugar, depletion of insulin-producing beta-cells of the pancreatic islets, and early death. The strain carries the misty mutation (Dock7m) to aid in early identification of homozygotes.
Strain Name BKS.Cg-Dock7m Leprdb/+ +/J
Background Strain DBA/J
SPF Yes
Research Application Diabetes
Target Information
Target Name Dock7; Lepr
Synonyms 3110056M06Rik, DEE23, EIEE23, LOC242555, m, mKIAA1771, ZIR2; CD295, Fa, LEP-R, Leprb, LEPRD, LEPROT, leptin receptor gene-related protein, Modb1, obese-like, obl, Obr, OB-R, OB-RGRP
Gene ID 85440; 3953
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