BKS.Cg- Lepob /J

BKS.Cg- Lepob /J

Cat. No.: DMM-001257

Status Age Sex
  • Live Mouse
  • Frozen Embryo
  • 4 weeks
  • 12 weeks
  • Customized Age
  • Male
  • Female
Model Overview
Model Description These mice carry a spontaneous mutation at the Lep locus on a C57BLKS/J background and are characterized by obesity, hyperphagia, hyperglycemia, glucose intolerance, and elevated plasma insulin. On the C57BLKS background homozygotes become severely diabetic with regression of islets and early death.
Strain Name BKS.Cg-Lepob/J
Background Strain C57BLKS/J
SPF Yes
Research Application Diabetes
Target Information
Target Name Lep
Synonyms LEPD, OB, obese, OBS
Gene ID 3952
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