Cat. No.: DMM-001296
| Status | Age | Sex |
|---|---|---|
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| Model Overview | |
|---|---|
| Model Description | This Sirt6BAC transgenic line exhibits eutopic and physiological overexpression of mouse SIRT6, resulting in enhanced insulin sensitivity in skeletal muscle and liver, as well as protection against aberrant glucose homeostasis and diet-induced type 2 diabetes mellitus. |
| Strain Name | C57BL/6-Tg(RP23-352G18)1Coppa/J |
| Background Strain | C57BL/6J |
| SPF | Yes |
| Research Application | Diabetes |
| Target Information | |
|---|---|
| Target Name | transgene insertion 1 |
| Synonyms | - |
| Gene ID | - |
Ace Therapeutics has a team of experts in the field of endocrine and metabolic research, aiming to provide innovative preclinical contract research solutions to cope with diabetes and its complications. We provide customized solutions and technical support, enabling the transformation of promising concepts into innovative treatments, thus accelerating the drug development process of diabetes.