C57BL/6-Tg(RP23-352G18)1Coppa/J

C57BL/6-Tg(RP23-352G18)1Coppa/J

Cat. No.: DMM-001296

Status Age Sex
  • Live Mouse
  • Frozen Embryo
  • 4 weeks
  • 12 weeks
  • Customized Age
  • Male
  • Female
Model Overview
Model Description This Sirt6BAC transgenic line exhibits eutopic and physiological overexpression of mouse SIRT6, resulting in enhanced insulin sensitivity in skeletal muscle and liver, as well as protection against aberrant glucose homeostasis and diet-induced type 2 diabetes mellitus.
Strain Name C57BL/6-Tg(RP23-352G18)1Coppa/J
Background Strain C57BL/6J
SPF Yes
Research Application Diabetes
Target Information
Target Name transgene insertion 1
Synonyms -
Gene ID -
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