Diabetic Wound Healing Models
logo

Diabetic Wound Healing Models

Diabetic wound healing models recapitulate delayed closure, impaired microcirculation, reduced granulation tissue formation, and biofilm susceptibility under chronic hyperglycemia. We leverage these validated models to provide customized efficacy evaluations of pro-healing, anti-inflammatory, and antimicrobial candidates.

This brochure provides a complete technical overview of our Diabetic Wound Healing Models, specifically designed to support preclinical efficacy evaluation of pro-healing, anti-inflammatory, and antimicrobial candidates.

This promotional material will provide you with a detailed presentation of:

  • Multi-species model portfolio
    We offer a variety of diabetic wound healing models across different animal species, including mice, rats, and pigs. Through multiple strategies such as pharmacological induction, spontaneous models, and diet-induced approaches, combined with full-thickness excision techniques, customized diabetic wound models can be established.
  • Comprehensive endpoints
    Thermal imaging for blood perfusion, histology (re-epithelialization, collagen deposition), and biofilm monitoring (observed in db/db mice under wound dressings from day 4).
  • Case data
    Comparative healing curves and wound photographs from db/db vs. C57BL/6 mice, showing delayed closure and the 9-14 day recovery window.
  • Complete pig study plan
    Diabetes induction protocol (>200 mg/dL glucose threshold, twice-daily ear vein sampling), glycemic maintenance, and post-wounding monitoring schedule.
  • Supporting platforms
    In vitro platform, histology (slide prep, H&E or Masson staining, imaging), and AAALAC-accredited animal facilities.

Download the brochure to access full model parameters, case datasets, and study schematics. Then contact us to tailor these models to your drug development program.

logo

Ace Therapeutics has a team of experts in the field of endocrine and metabolic research, aiming to provide innovative preclinical contract research solutions to cope with diabetes and its complications. We provide customized solutions and technical support, enabling the transformation of promising concepts into innovative treatments, thus accelerating the drug development process of diabetes.

Contact Info
Copyright © Ace Therapeutics. All Rights Reserved.
Top