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FVB/N-Tg(Ins2-IAPP)RHFSoel/J
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FVB/N-Tg(Ins2-IAPP)RHFSoel/J

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Cat. No.: DMM-001271

Status Age Sex
  • Live Mouse
  • Frozen Embryo
  • 4 weeks
  • 12 weeks
  • Customized Age
  • Male
  • Female
Model Overview
Model Description These RIPHAT transgenic mice express human islet amyloid polypeptide (h-IAPP) under the regulatory control of the rat insulin II promoter and may be useful in studying the beta-cell destruction and islet amyloid deposition associated with non-insulin-dependent diabetes mellitus (NIDDM) or Type II diabetes, as well as beta-cell apoptosis and characteristics of the endoplasmic reticulum (ER) stress pathway.
Strain Name FVB/N-Tg(Ins2-IAPP)RHFSoel/J
Background Strain FVB/N
SPF Yes
Research Application Diabetes
Target Information
Target Name Tg(Ins2-IAPP)RHFSoel
Synonyms RIPHAT,RIPHAT line RHF,Tg(IAPP)6Jdm
Gene ID -
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