STOCK Ank2^tm2Bnt /J

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STOCK Ank2^tm2Bnt /J

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STOCK Ank2^tm2Bnt /J

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Cat. No.: DMM-001256

Status	Age	Sex
Live Mouse Frozen Embryo	4 weeks 12 weeks Customized Age	Male Female

Model Overview
Model Description	Ankb^{L1622I/L1622I} (Ank2) knock-in mice develop a metabolic syndrome characterized by early-onset pancreatic β cell dysfunction and age- or diet-dependent increases in adiposity and insulin resistance. Tissue-specific ANK2 deficiency is also observed.
Strain Name	STOCK Ank2tm2Bnt/J
Background Strain	C57BL/6J
SPF	Yes
Research Application	Diabetes

Target Information
Target Name	Ank2
Synonyms	ANK-2, Ank3, ankyrin B, Ankyrin-2
Gene ID	287

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

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Ace Therapeutics has a team of experts in the field of endocrine and metabolic research, aiming to provide innovative preclinical contract research solutions to cope with diabetes and its complications. We provide customized solutions and technical support, enabling the transformation of promising concepts into innovative treatments, thus accelerating the drug development process of diabetes.

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