Unlock Insights Into Stroke Research With Our Blood Injection Intracerebral Hemorrhage Model Case Study

At Ace Therapeutics, we are dedicated to accelerating the discovery and development of innovative treatments for stroke and brain injury. Our blood injection ICH model provides a customizable platform for investigating the complex mechanisms underlying cerebral hemorrhage and for evaluating therapeutic candidates with translational potential.

What You'll Find Inside

• Detailed overview of the surgical and modeling methods, including stereotactic blood injection techniques.
• Representative gross anatomy and TTC staining results demonstrating hematoma formation and lesion progression.
• Experimental grouping and validation data confirming model reliability.

Comprehensive Readouts and Analytical Capabilities

• Hemorrhagic injury volume and ventricular volume: TTC staining, Nissl staining.
• Brain edema evaluation: Wet-dry weight ratio method.
• Neurological scores and behavioral assessment: Neurologic deficit score, wire-hanging test, tail suspension test (TST), novel object recognition test, etc.
• Histopathology: H&E staining, immunohistochemistry (IHC).
• Brain imaging: MRI, PET-CT, and laser speckle contrast imaging.
• Protein and molecular analyses: Western blotting, PCR, and multiplex cytokine profiling.

By downloading this case study, you'll see how our blood injection ICH model can accelerate your stroke research and strengthen the translational impact of your therapeutic programs.

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