Overview of In Vitro Oxygen Glucose Deprivation (OGD) Models

Unlock Insights into Stroke Research | Specialized Experimental Model Solutions

At Ace Therapeutics, we are advancing preclinical stroke research with our in vitro OGD Models, a powerful and reproducible platform designed to mimic ischemic conditions in the brain.

Applications in Preclinical Stroke Research

Our in vitro OGD models are ideal for:

• Screening and evaluating candidate compounds for neuroprotection
• Modeling neuronal injury and death pathways under ischemic stress
• Studying reperfusion-induced damage and oxidative stress mechanisms
• Investigating inflammatory cascades and cytokine regulation in stroke pathology

Each model can be tailored to your experimental needs, with vehicle control, positive control, and candidate compound conditions for robust comparative analysis.

Comprehensive Readouts and Analytical Capabilities

• Cell viability assays: MTT, LDH
• Apoptosis assays: Annexin V/PI staining, Caspase-3 activation
• Inflammatory response assays: ELISA, qPCR for cytokines
• Protein and molecular analyses: Western blotting, PCR, and immunofluorescence

Why Choose Ace Therapeutics' In Vitro OGD Models?

• High reproducibility and physiological relevance
• Customizable protocols to model ischemia and reperfusion
• Comprehensive analytical data
• Accelerated screening and validation for preclinical therapeutics
• Expert scientific collaboration for every project

Download the brochure to explore how our in vitro OGD models can enhance the reliability and translational impact of your preclinical stroke studies.

You might be interested in...