Advance Intracerebral Hemorrhage Research with a Validated Collagenase-Induced ICH Model
Intracerebral hemorrhage (ICH) accounts for a relatively small proportion of stroke cases but is responsible for a disproportionately high burden of mortality and long-term disability. Robust preclinical models are essential for evaluating novel interventions and understanding the mechanisms of secondary brain injury.
Our collagenase-induced ICH mouse model reproduces critical pathological events, including vascular disruption, hematoma expansion, neuroinflammation, and cerebral edema, providing a powerful platform for therapeutic evaluation.
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A systematic introduction to Ace Therapeutics' preclinical stroke research capabilities and cutting-edge technology platforms.
Ace Therapeutics provides customized stroke models and technology platforms to support preclinical stroke research.
The collagenase-induced ICH model reliably reproduces key pathological features, including microvascular rupture, mixed parenchymal hemorrhage, inflammation, and brain edema.
Photochemical thrombosis is a method for the induction of ischemic stroke in the cerebral cortex, which aids in stroke mechanism and therapy development.