Discover the Power of DIO Mice in Type 2 Diabetes Research

Unlock the secrets of Type 2 Diabetes with Ace Therapeutics' innovative DIO (Diet-Induced Obesity) Mice model. This cutting-edge animal model is specifically designed to simulate the symptoms of human obesity and diabetes, providing researchers with an unparalleled tool for understanding the pathogenesis of these complex diseases.

Why Choose DIO Mice?

• Realistic Simulation: DIO Mice are selectively bred for susceptibility to obesity and diabetes, ensuring a highly accurate representation of human conditions. By feeding them a high-fat diet starting from 6 weeks of age, researchers can observe symptoms such as weight gain, elevated blood sugar, and impaired glucose tolerance.
• Optimal Modeling: The DIO model requires 8-12 weeks for optimal results, making it an efficient choice for time-sensitive studies. With just 6 mice per group, researchers can achieve statistically significant outcomes, as demonstrated in our case study with 297 mice in the high-fat diet group and 79 in the normal diet group.
• Proven Results: Our research shows that after feeding with a 60% high-fat diet, the body weight of DIO Mice significantly increased compared to the control group. Moreover, these mice exhibited significant impairment in glucose tolerance, as evidenced by their blood glucose levels and AUC of OGTT.

Download our detailed guide on the Application of DIO Mice today and discover how this model can revolutionize your understanding of obesity, diabetes, and related metabolic diseases.

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