B6.129P2(Cg)- Akt2^tm1.1Mbb /J

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B6.129P2(Cg)- Akt2^tm1.1Mbb /J

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B6.129P2(Cg)- Akt2^tm1.1Mbb /J

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Cat. No.: DMM-001276

Status	Age	Sex
Live Mouse Frozen Embryo	4 weeks 12 weeks Customized Age	Male Female

Model Overview
Model Description	Mice homozygous for this Akt2 (thymoma viral proto-oncogene 2) mutant allele develop insulin resistance, hyperglycemia, impaired glucose tolerance, abnormal glucose uptake in muscle tissue, increased pancreatic beta-cell mass, and diabetes.
Strain Name	B6.129P2(Cg)-Akt2tm1.1Mbb/J
Background Strain	129P2/OlaHsd
SPF	Yes
Research Application	Diabetes

Target Information
Target Name	Akt2
Synonyms	2410016A19Rik, HIHGHH, PKB, PKBB, PKBbeta, PRKBB, RAC-BETA
Gene ID	208

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

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Ace Therapeutics has a team of experts in the field of endocrine and metabolic research, aiming to provide innovative preclinical contract research solutions to cope with diabetes and its complications. We provide customized solutions and technical support, enabling the transformation of promising concepts into innovative treatments, thus accelerating the drug development process of diabetes.

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