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Blood–Brain Barrier (BBB) Chip Model

Ace Therapeutics' BBB chip model is a human-relevant microfluidic platform that recreates the key structural and functional features of the human blood–brain barrier, enabling more predictive CNS research and drug development.
Case Studies

Accelerate CNS and Stroke Research with a Human-Relevant BBB Chip Model

The blood–brain barrier remains one of the most significant challenges in CNS drug development. Traditional in vitro models often fail to accurately predict drug transport, permeability, and barrier responses, leading to costly delays and poor clinical translation.

Download our case study to discover how Ace Therapeutics' Blood–Brain Barrier (BBB) Chip Model provides a physiologically relevant platform for evaluating drug transport, barrier integrity, and therapeutic delivery across the BBB.

Download this case study to see:

  • A validated BBB-on-a-chip platform built with human-derived cells
  • Evidence of tight junction formation and functional barrier properties
  • Drug transport and permeability assessment capabilities
  • Advanced readouts including TEER, permeability assays, imaging, and biomarker analysis
  • Applications for stroke research and CNS therapeutic development

Whether you are developing small molecules, biologics, antibodies, or novel delivery systems, this case study provides valuable insights into leveraging BBB-on-a-chip technology for more informed decision-making.