Diabetes Drug R&D Services ace

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* Services or Products of Interest In Vivo Efficacy Assessment of Antidiabetic Drugs
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* All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
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In Vivo Efficacy Assessment of Antidiabetic Drugs

Ace Therapeutics provides one-stop services for in vivo efficacy assessment. We are committed to providing tailor-made solutions to our clients and contributing to the advancement of innovative drug discovery in the field of diabetes. With reliable in vivo models and efficient assays, we will maximize your antidiabetic drug discovery program.

Our In Vivo Efficacy Assessment Services of Antidiabetic Drugs

Ace Therapeutics' in vivo efficacy assessment service provides comprehensive in vivo efficacy and pharmacological data through advanced animal models, supporting clients globally. Our one-stop solution allows us to assess the efficacy and safety of antidiabetic drugs at various levels of molecular biology, histopathology, and biochemical analyses.

Highlights of our in vivo efficacy assessment services include:

Simulating the pharmacological actions of antidiabetic drugs in organisms and to clarify the mechanism of action of potential drugs in vivo.
Providing information on the efficacy, safety, and tolerability of antidiabetic drugs, and provide a basis for subsequent drug development.

In Vivo Efficacy Assays of Antidiabetic Drugs We Offer

Ace Therapeutics provides end-to-end experimental design to fully evaluate the in vivo efficacy of your antidiabetic drug candidate. We combine in vivo metabolic analyses with molecular biology, histology, and imaging analyses in an effort to provide comprehensive in vivo data to support your antidiabetic drug development.

Random blood glucose and fasting blood glucose tests
Oral glucose tolerance test (OGTT)
Insulin tolerance test (ITT)
Biochemical analysis (Measurements of total cholesterol (TC) and triglycerides (TG) in serum samples, and glycated hemoglobin (HbA1c) in plasma samples.)
Molecular biology analyses (Detect the effects of antidiabetic drugs on diabetes-related blood glucose, lipids, and insulin signaling pathways.)
Histopathological analysis (Histopathological microscopic observation of the effects of antidiabetic drugs on the pancreas and liver of animals.)

How Can Our In Vivo Efficacy Assessment Service Help Your Antidiabetic Drug Development?

Our in vivo efficacy assessment service provides the data required to make critical decisions at different key stages of antidiabetic drug development.

Antidiabetic drug screening	Antidiabetic drug optimization	Preclinical assessment of antidiabetic drugs
In vivo efficacy assessment based on in vitro evaluation results to further validate the efficacy of antidiabetic drug candidates.	Based on the results of in vivo efficacy assessment, we optimize the structure of the drug to help our clients screen better antidiabetic drug candidates.	Combining the results of in vivo and in vitro assessment to comprehensively assess the efficacy, safety and pharmacokinetic properties of antidiabetic drug candidates.

Advantages of Our In Vivo Efficacy Assessment Services

Our multifaceted strengths can accelerate your antidiabetic drug development process.

*Various customized in vivo* models**	*Customized in vivo* research strategies**	Extensive experience
We have a wealth of in vivo models and are constantly developing new animal models of diabetes to meet the diverse needs of our clients.	We provide customized in vivo study strategies and use reference drugs and positive controls for quality assurance.	We have extensive experience in assessing different types and mechanisms of antidiabetic drug candidates, including small molecules, antibodies, peptides and proteins, nucleic acid drugs, vaccines and combinations thereof.

Ace Therapeutics is committed to pooling our diabetes expertise and advanced assay technologies to perform comprehensive in vivo efficacy assessment of antidiabetic drug candidates. Our multidisciplinary experts ensure rapid progress of your project by providing proof of concept for your antidiabetic drug candidates. Please feel free to contact us for more detailed information.

Reference

Wang, H.; et al. In Vitro and In Vivo Evaluation of Antidiabetic Properties and Mechanisms of Ficus tikoua Bur. Nutrients. 2022, 14(20): 4413.

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

Related Services

In Vitro Efficacy Assessment of Antidiabetic Drugs