Ace Therapeutics provides one-stop in vivo pharmacokinetic services to help clients accelerate their antidiabetic drug development. We are committed to providing appropriate experimental designs, reliable dose-response studies, and advice on potential dose ranges based on client needs. With reliable in vivo models and efficient assay services, we strive to optimize your antidiabetic drug development pipeline.
Pharmacokinetics focuses on the dynamic processes of drug metabolism within the body, encompassing absorption, distribution, metabolism, and excretion (ADME). It is instrumental in guiding the design of new antidiabetic drugs, optimizing dosing regimens, improving dosage forms, and providing highly effective, low-toxicity (or low side-effect) drugs. We offer pharmacokinetic testing, including:
Ace Therapeutics performs biodistribution and pharmacokinetic studies of antidiabetic drugs in preclinical animal models. We analyze your antidiabetic drug and its metabolites by distribution in different tissues, organs and blood samples collected at different time points in order to provide you with detailed pharmacokinetic data. We ensure reliable and actionable insights for your development programs.
Equipment | Applications | Advantages |
---|---|---|
LC-MS/MS: API 5500, API 5000, API 4000, API 4000 Q-Trap | Identification and quantitative analysis of metabolites of antidiabetic drugs. |
|
GC-MS/TCD/FID/ECD/NPD | Analysis of volatile drugs and their metabolites. |
|
HPLC-VWD/DAD/PDA/FLD | Detection of compounds with UV absorption. |
|
ICP-MS/AAS/AFS | Detect metal elements with fluorescent properties and their compounds. |
|
Ace Therapeutics is committed to helping our clients better understand the behavior of antidiabetic drugs in vivo, optimize drug development and application, improve therapeutic efficacy and reduce the risk of adverse effects through our high-quality services. If you need a partner with extensive knowledge in the pharmacokinetics of antidiabetic drugs, please contact us. We will provide more details.
Ace Therapeutics has a team of experts in the field of endocrine and metabolic research, aiming to provide innovative preclinical contract research solutions to cope with diabetes and its complications. We provide customized solutions and technical support, enabling the transformation of promising concepts into innovative treatments, thus accelerating the drug development process of diabetes.