BBB Models Portfolio

Ace Therapeutics offers a broad BBB models product portfolio including 3D organoid BBB models, 3D BBB models culture substrate, and cell lines for BBB modeling to support your research relevant to BBB, whether it be studying BBB development, drug delivery across the BBB, or investigating neurodegenerative diseases.

BBB Models Introduction

The BBB is part of the neurovascular unit and is composed of endothelial cells (ECs), astrocytes (ACs), pericytes (PCs), neurons, and microglia. Its complexity provides multiple options for constructing BBB models with varying degrees of physiological accuracy.

• Cell line model: Use endothelial cell lines cultured in vitro to simulate the structure and function of the BBB, which are simple to use and low-cost.
• Co-culture model: Culture endothelial cells and astrocytes or other supporting cells together to better simulate the structure and function of the BBB, thereby providing greater physiological accuracy and predictability.
• 3D organoid model: Endothelial cells, astrocytes and other related cells are organized on in vitro organs to simulate a more realistic BBB structure and function, which can provide a closer simulation of in vivo conditions and facilitate drug screening and toxicity studies.
• Animal model: Constructed through the use of transgenic technology with high biological authenticity.

Ace Therapeutics's BBB Models Portfolio Superiorities:

• A variety of products, both in vivo and in vitro BBB models, are available to meet different research needs.
• Strict quality control measures, including the test of barrier integrity, transport properties and cell viability to ensure functionality and reliability.
• Extensive supporting products for BBB modeling and analysis.
• Professional after-sales support from experts with extensive knowledge and experience in BBB research.

Click on the Links to Access Our BBB Models Product Portfolio: