Products
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- BBB DamageCategories
- Neurotransmitter Antibodies & Receptor Antibodies
- Ionotropic Receptor AntibodiesMetabotropic Receptor AntibodiesNeurotransmitter AntibodiesTransporter AntibodiesSignal Channel Antibodies
- Calcium Channel AntibodiesChloride Channel AntibodiesDense-Core Vesicles AntibodiesNitric Oxide Channel AntibodiesStroke Pathology Antibodies
- Neurogenesis AntibodiesNeuronal Growth & Development AntibodiesNeuronal Growth & Development AntibodiesNeuronal Metabolism AntibodiesSignal Transduction AntibodiesStroke-Related Cell Markers Antibodies
- Glial Cell Marker AntibodiesNeural Stem Cell Marker AntibodiesNeuron Marker AntibodiesSynaptic Marker AntibodiesCell Death and ApoptosisNeuroinflammationNeuronal Damage and RepairOxidative StressVascular Mechanisms
- 3D BBB Models
- Organ-on-a-Chip BBB ModelsTranswell Models3D BBB Models Culture Substrate
- 3D HydrogelsCollagensAnmial BBB ModelsCell Lines for BBB Modeling
- Immortalized CellsPrimary CellsStem Cells
Collagens
Collagen is the main component of connective tissue and is abundant in mammals. It is the most widely used extracellular matrix in 3D cell culture to promote cell attachment, growth, differentiation, migration and tissue morphogenesis.
In the 3D BBB model, collagen is used as the main component of the cell culture matrix to provide a support and attachment matrix for cells, thus supporting the simulation study of complex cell interactions and biological processes.
The 3D BBB model is a three-dimensional cell culture model that simulates the blood-brain barrier and is used to study related neurobiology and drug delivery issues. In order to reproduce real physiological conditions, the 3D BBB model uses a collagen matrix to culture brain vascular endothelial cells and other related cells to form a microenvironment with blood-brain barrier function. Collagen plays different roles when creating a three-dimensional blood-brain barrier (BBB) model culture matrix.
- Has good biocompatibility and can promote cell attachment and growth.
- Has a three-dimensional structure and can simulate the characteristics of real tissues.
- Helps form the structure and function of brain vascular endothelial cells and related cells.
It is worth noting that the choice of collagen for the 3D BBB model culture matrix should be based on the specific requirements of the study and the desired matrix functionality. Furthermore, combining different types of collagen or using mixtures of collagen with other ECM components can further enhance the biomimetic properties and functionality of BBB model culture substrates.
Ace Therapeutics produces and supplies different types of collagen to help you construct an ideal, stable 3D BBB model in vitro that meets your research needs.
Cat.# Name Description Price BBM-3C-016 Bovine Collagen Type VI, Lyophilized, 0.1mg Bovine Collagen Type VI, Lyophilized, 0.1mg from Ace Therapeutics is purified from the bovine placenta. The product is the major collagenous component of microfibrils in elastic fibers and in a larger variety of tissues, which consist of two α-chains of ca.inquiry BBM-3C-017 Bovine Collagen Type I (Atelocollagen) , 30 mg Bovine Collagen Type I (Atelocollagen) from Ace Therapeutics is purified from bovine tendons. Type I collagen is found in connective tissues and is the major component of tensile strength of the extracellular matrix (ECM). The product is widely used as a thin layer on tissue-culture surfaces to enhance the attachment and proliferation of a variety of cells including endothelial cells, fibroblasts, hepatocytes, epithelial cells, etc. In addition, the product can self-assemble into a 3-D supramolecular gel in vitro as an ideal biological scaffold.inquiry BBM-3C-018 Mouse Collagen Type I (Atelocollagen), 1 mg Mouse Collagen Type I (Atelocollagen) from Ace Therapeutics is purified from the mouse tail tendon. Type I collagen is found in connective tissues and is the major component of tensile strength of the extracellular matrix (ECM). The product is widely used as a thin layer on tissue-culture surfaces to enhance the attachment and proliferation of a variety of cells including endothelial cells, fibroblasts, hepatocytes, epithelial cells, etc. In addition, the product can self-assemble into a 3-D supramolecular gel in vitro as an ideal biological scaffold.inquiry BBM-3C-019 Rat Collagen Type I (Atelocollagen), 30 mg Rat Collagen Type I (Atelocollagen) from Ace Therapeutics is purified from the rat tail tendon. Type I collagen is found in connective tissues and is the major component of tensile strength of the extracellular matrix (ECM). The product is widely used as a thin layer on tissue-culture surfaces to enhance the attachment and proliferation of a variety of cells including endothelial cells, fibroblasts, hepatocytes, epithelial cells, etc. In addition, the product can self-assemble into a 3-D supramolecular gel in vitro as an ideal biological scaffold.inquiry BBM-3C-020 Bovine Collagen Type I and III, 10 mg Bovine Collagen Type I and III, 10 mg from Ace Therapeutics is purified from calf skin. Type I collagen is the most abundant collagen and is found in connective tissues including tendons, ligaments, dermis, and blood vessels. Type III collagen is the second most abundant collagen in tissues and is found most commonly in tissues exhibiting elastic properties such as skin, lungs, intestinal walls, and walls of blood vessels, which resembles other fibrillar collagens in structure and function.inquiry BBM-3C-021 Canine Collagen Type I and III, 10 mg Canine Collagen Type I and III, 10 mg from Ace Therapeutics is purified from canine collagen. Type I collagen is the most abundant collagen and is found in connective tissues including tendons, ligaments, dermis, and blood vessels. Type III collagen is the second most abundant collagen in tissues and is found most commonly in tissues exhibiting elastic properties such as skin, lungs, intestinal walls, and walls of blood vessels, which resembles other fibrillar collagens in structure and function.inquiry BBM-3C-022 Mouse Collagen Type I and III, 5 mg Mouse Collagen Type I and III, 5 mg from Ace Therapeutics is purified from rom tail tendons of the mouse. Type I collagen is the most abundant collagen and is found in connective tissues including tendons, ligaments, dermis, and blood vessels. Type III collagen is the second most abundant collagen in tissues and is found most commonly in tissues exhibiting elastic properties such as skin, lungs, intestinal walls, and walls of blood vessels, which resembles other fibrillar collagens in structure and function.inquiry BBM-3C-023 Porcine Collagen Type I and III, 10 mg Porcine Collagen Type I and III, 10 mg from Ace Therapeutics is purified from pig’s tissue. Type I collagen is the most abundant collagen and is found in connective tissues including tendons, ligaments, dermis, and blood vessels. Type III collagen is the second most abundant collagen in tissues and is found most commonly in tissues exhibiting elastic properties such as skin, lungs, intestinal walls, and walls of blood vessels, which resembles other fibrillar collagens in structure and function.inquiry BBM-3C-024 Rat Collagen Type I and III, 10 mg Rat Collagen Type I and III, 10 mg from Ace Therapeutics is purified from rat tissue. Type I collagen is the most abundant collagen and is found in connective tissues including tendons, ligaments, dermis, and blood vessels. Type III collagen is the second most abundant collagen in tissues and is found most commonly in tissues exhibiting elastic properties such as skin, lungs, intestinal walls, and walls of blood vessels, which resembles other fibrillar collagens in structure and function.inquiry BBM-3C-025 Bovine Collagen Type I, 10 mg Bovine Collagen Type I, 10 mg from Ace Therapeutics is purified from bovine skin. Type I collagen is found in connective tissues and is the major component of tensile strength of the extracellular matrix (ECM). The product is widely used as a thin layer on tissue-culture surfaces to enhance the attachment and proliferation of a variety of cells including endothelial cells, fibroblasts, hepatocytes, epithelial cells, etc. In addition, the product can self-assemble into a 3-D supramolecular gel in vitro as an ideal biological scaffold.inquiry BBM-3C-026 Goat Collagen Type I, 10 mg Goat Collagen Type I, 10 mg from Ace Therapeutics is purified from goat tissue. Type I collagen is found in connective tissues and is the major component of tensile strength of the extracellular matrix (ECM). The product is widely used as a thin layer on tissue-culture surfaces to enhance the attachment and proliferation of a variety of cells including endothelial cells, fibroblasts, hepatocytes, epithelial cells, etc. In addition, the product can self-assemble into a 3-D supramolecular gel in vitro as an ideal biological scaffold.inquiry BBM-3C-027 Mouse Collagen Type I, 1 mg Mouse Collagen Type I, 1 mg from Ace Therapeutics is purified from mouse tail tendon. Type I collagen is found in connective tissues and is the major component of tensile strength of the extracellular matrix (ECM). The product is widely used as a thin layer on tissue-culture surfaces to enhance the attachment and proliferation of a variety of cells including endothelial cells, fibroblasts, hepatocytes, epithelial cells, etc. In addition, the product can self-assemble into a 3-D supramolecular gel in vitro as an ideal biological scaffold.inquiry BBM-3C-028 Porcine Collagen Type I, 30 mg Porcine Collagen Type I, 30 mg from Ace Therapeutics is purified from porcine tendon. Type I collagen is found in connective tissues and is the major component of tensile strength of the extracellular matrix (ECM). The product is widely used as a thin layer on tissue-culture surfaces to enhance the attachment and proliferation of a variety of cells including endothelial cells, fibroblasts, hepatocytes, epithelial cells, etc. In addition, the product can self-assemble into a 3-D supramolecular gel in vitro as an ideal biological scaffold.inquiry BBM-3C-029 Bovine Collagen Type III, 10 mg Bovine Collagen Type III, 10 mg from Ace Therapeutics is purified from bovine (calf ) skin. Type III collagen is the second most abundant collagen in tissues and is found most commonly in tissues exhibiting elastic properties such as skin, lungs, intestinal walls, and walls of blood vessels, which resembles other fibrillar collagens in structure and function.inquiry BBM-3C-030 Bovine Collagen Type V (Atelocollagen), 1 mg Bovine Collagen Type V (Atelocollagen), 1 mg from Ace Therapeutics is purified from bovine placenta.inquiry All of our products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
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