CCR2 covalent NAM (AC137)

Cat.#: ASSD-137

ASSD-137

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Specifications


Description Chemokine CCR2 covalent negative allosteric modulator (NAM) binds intracellularly and forms a covalent bond with one of three proximal cysteine residues of CCR2. Apparent pKi values at CCR2 are 8.7 and 9.2 (after 4h), where a Ki shift indicates a covalent mode of action.
Size 50 μg
Chemical Name 2-[[4-[4-Chloro-2-[[4-chloro-3-(trifluoromethyl)phenyl]sulfonylamino]phenoxy]benzoyl]amino]ethyl thiocyanate
Molecule Weight 590.4
Molecular formula C23H16Cl2F3N3O4S2
PubChem identifier 162666730
Purity >95%
Solubility Soluble in DMSO
Storage Store at -20° C
Shipping Shipped at 4°C

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