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Fluorescent β2 antagonist [(S)-propranolol-red] (AC123)
Cat.#: ASSD-123
Specifications
| Description | Competitive fluorescent β2-adrenoceptor antagonist. Displays selectivity for β2 over β1 and β3 (apparent KD values are 9.21, 7.76 and 7.09 respectively). Antagonizes the activity of isoprenaline, a non-selective β-adrenoceptor agonist. Exhibits no intrinsic agonist activity. |
| Synonyms | β2-633-AN2 |
| Size | 500 μg |
| Applications | For imaging at β1 / β2 / β3 adrenoceptors use solutions up to 100 nM. |
| Molecule Weight | 894 |
| Purity | >95% |
| Solubility | Soluble in DMSO |
| Excitation | 633 nm |
| Emission | 650 nm |
| Storage | Store at -20° C |
| Shipping | Shipped at 4°C |
| Important | We strongly recommend storing this product away from light and briefly sonicating the sample when using to ensure it is fully dissolved and the solution is homogeneous. However, we do not recommend using the product after subjecting it to repetitive freeze-thaw cycles. |
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are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.