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JC-1 (AC135)
Cat.#: ASSD-135
Specifications
| Description | JC-1 is a Mitochondrial membrane potential indicator/dye that is widely used in apoptosis studies to monitor mitochondrial health. The product is used as an indicator of mitochondrial membrane potential in neurons and also intact tissues and isolated mitochondria, allowing both qualitative visualization and quantitative detection. Interpretation of Results • At low concentrations (due to low mitochondrial membrane potential), JC-1 is predominantly a monomer that yields green fluorescence with emission of 530±15 nm. • At high concentrations (due to high mitochondrial membrane potential), the dye aggregates yielding a red to orange colored emission (590±17.5 nm). Depolarization is indicated by a decrease the aggregate fluorescent count and hyperpolarization is indicated by an increase. |
| Size | 5 mg |
| Chemical Name | 5,5',6,6'-Tetrachloro-1,1',3,3'-tetraethylbenzimidazolylcarbocyanine iodide |
| Molecule Weight | 652.2 |
| Molecular formula | C25H27Cl4IN4 |
| Purity | >95% |
| Storage | Store at -20° C |
| Shipping | Shipped at 4°C |
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are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.