Cat.#: ASSD-140
| Description | A2B covalent ligand selectively targets lysine residue(s) on the receptor and binds persistently in radioligand displacement and wash-out assays, allowing for novel ways to interrogate the A2BAR. Apparent pKi values at A2BARs are 8.10 and 9.17 (after 4h), where a Ki shift indicates a covalent mode of action. Displays ~100 -fold selectivity for A2B compared to A1, A2A and A3 receptors. |
| Size | 50 μg |
| Chemical Name | 4-(2,6-dioxo-1-propyl-2,3,6,7-tetrahydro-1H-purin-8-yl)benzenesulfonyl fluoride |
| Molecule Weight | 352.3 |
| Molecular formula | C14H13FN4O4S |
| Purity | >95% |
| Solubility | Soluble in DMSO |
| Storage | Store at -20° C |
| Shipping | Shipped at 4°C |
| Cat.# | Name | Size | Price |
|---|---|---|---|
| ASSD-203 | Bis(2,2′-bipyridine)-4,4′-dicarboxybipyridine-ruthenium di(N-succinimidyl ester) bis(hexafluorophosphate) (AC203) | 5 mg | inquiry |
| ASSD-113 | Thionin acetate salt (AC113) | 5 g | inquiry |
| ASSD-201 | Fluoresceinamine Hydrochloride Isomer 1 (AC201) | 2 g | inquiry |
| ASSD-119 | Fluorescent adenosine agonist [NECA] (AC119) | 500 μg | inquiry |
| ASSD-184 | BTA-1 (AC184) | 10 mg | inquiry |
| ASSD-170 | BAPTA-AM (AC170) | 25 mg | inquiry |
| ASSD-178 | 5-(Iodoacetamido)fluorescein (AC178) | 25 mg, 100 mg, 250 mg | inquiry |
| ASSD-117 | Annexin V-PE Apoptosis Staining / Detection Kit (AC117) | 1 kit, 100 tests | inquiry |
| ASSD-131 | Calcein Blue (AC131) | 1 mg | inquiry |
| ASSD-197 | Sulforhodamine 101 acid chloride (AC197) | 10 mg, 25 mg | inquiry |
Ace Therapeutics is a global leading provider of stroke research services. We are committed to accelerating progress in stroke research and drug development.